Research Paper Volume 13, Issue 2 pp 2668—2680

Notch-1 promotes the malignant progression of osteosarcoma through the activation of cell division cycle 20

Notch-1 upregulation elevated viability and suppressed apoptosis. (A) Viability was elevated after Notch-1 upregulation, as determined by MTT assay. *P B) Apoptosis was inhibited after Notch-1 upregulation. (C) Invasion was enhanced after Notch-1 upregulation, as determined by Transwell assay.

Figure 3. Notch-1 upregulation elevated viability and suppressed apoptosis. (A) Viability was elevated after Notch-1 upregulation, as determined by MTT assay. *P < 0.05 vs control cDNA. (B) Apoptosis was inhibited after Notch-1 upregulation. (C) Invasion was enhanced after Notch-1 upregulation, as determined by Transwell assay.