Research Paper Volume 13, Issue 3 pp 3645—3660

Enrichment of branched chain amino acid transaminase 1 correlates with multiple biological processes and contributes to poor survival of IDH1 wild-type gliomas

BCAT1 is correlated with glycolysis process in gliomas. (A, B) The correlation of BCAT1 with glycolytic enzymes in TCGA and CGGA datasets. (C, D) Heatmap showing the mRNA expression of BCAT1 and related glycolytic enzymes in IDH1 wild-type and mutant gliomas based on TCGA and CGGA datasets. (E–J) Survival plots for BCAT1 correlated glycolytic enzymes in TCGA glioma patients. (K–P) Survival plots for BCAT1 correlated glycolytic enzymes in CGGA glioma patients.

Figure 4. BCAT1 is correlated with glycolysis process in gliomas. (A, B) The correlation of BCAT1 with glycolytic enzymes in TCGA and CGGA datasets. (C, D) Heatmap showing the mRNA expression of BCAT1 and related glycolytic enzymes in IDH1 wild-type and mutant gliomas based on TCGA and CGGA datasets. (EJ) Survival plots for BCAT1 correlated glycolytic enzymes in TCGA glioma patients. (KP) Survival plots for BCAT1 correlated glycolytic enzymes in CGGA glioma patients.