Research Paper Volume 13, Issue 3 pp 4024—4044

Identification of candidate genes encoding tumor-specific neoantigens in early- and late-stage colon adenocarcinoma

Mutational profile and KEGG pathway analysis of candidate COAD neoantigen-related DEGs. (A) Mutation frequency data. The percentage of patients harboring the color-coded variations listed at the bottom are indicated on the left and right sides. (B) KEGG pathways enriched in the 24 candidate neoantigen-related genes. Red and green boxes indicate up- and down-regulated genes, respectively.

Figure 7. Mutational profile and KEGG pathway analysis of candidate COAD neoantigen-related DEGs. (A) Mutation frequency data. The percentage of patients harboring the color-coded variations listed at the bottom are indicated on the left and right sides. (B) KEGG pathways enriched in the 24 candidate neoantigen-related genes. Red and green boxes indicate up- and down-regulated genes, respectively.