Research Paper Volume 13, Issue 1 pp 1458—1472

CHIP protects against MPP+/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease

In MPTP-treated NES-CHIP mice and the littermates wild-type mice, proteins in SNpc and striatum were detected by Western blot. (A) Under the action of MPTP, the level of Drp1 increased significantly in wildtype mice than that in NES-CHIP littermates. (B–F) Quantitative analysis of the blots. *P

Figure 10. In MPTP-treated NES-CHIP mice and the littermates wild-type mice, proteins in SNpc and striatum were detected by Western blot. (A) Under the action of MPTP, the level of Drp1 increased significantly in wildtype mice than that in NES-CHIP littermates. (BF) Quantitative analysis of the blots. *P<0.05.