Research Paper Volume 13, Issue 1 pp 1458—1472

CHIP protects against MPP+/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease

Mitochondrial morphology change of each group. (A) Mitochondria were labeled with MitoTracker Red. MPP+ treatment lead to fragmentation of mitochondria, while CHIP overexpression improved the mitochondria disruption. (B) Histogram of form factor analysis. *P

Figure 4. Mitochondrial morphology change of each group. (A) Mitochondria were labeled with MitoTracker Red. MPP+ treatment lead to fragmentation of mitochondria, while CHIP overexpression improved the mitochondria disruption. (B) Histogram of form factor analysis. *P<0.05.