Research Paper Volume 13, Issue 3 pp 4357—4369

The hepatic microenvironment promotes lung adenocarcinoma cell proliferation, metastasis, and epithelial–mesenchymal transition via METTL3-mediated N6-methyladenosine modification of YAP1

The hepatic inflammatory microenvironment promoted the epithelial–mesenchymal transition (EMT) of lung adenocarcinoma cells. (A) The expression level of E-cadherin and vimentin in A549 and H1975 cells was detected by laser confocal scanning microscopy. (B) Changes in CDH1 and VIM mRNA expression in A549 and H1975 cells were detected by real-time PCR (*P

Figure 2. The hepatic inflammatory microenvironment promoted the epithelial–mesenchymal transition (EMT) of lung adenocarcinoma cells. (A) The expression level of E-cadherin and vimentin in A549 and H1975 cells was detected by laser confocal scanning microscopy. (B) Changes in CDH1 and VIM mRNA expression in A549 and H1975 cells were detected by real-time PCR (*P<0.05 versus the control group).