Research Paper Volume 13, Issue 2 pp 2912—2940

Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer

Network analysis. (A) C-T network. (B) T-P network. Yellow nodes represent potential targets; blue circles represent active ingredients of Epimedium; squares represent targets-related pathways; and edge represents the interaction between them. Node size is proportional to its degree. (C) P-D chord diagram. The circle represents the selected pathways and diseases, and the color of the bands within the circle reflects the relationship between the pathways and the diseases.

Figure 4. Network analysis. (A) C-T network. (B) T-P network. Yellow nodes represent potential targets; blue circles represent active ingredients of Epimedium; squares represent targets-related pathways; and edge represents the interaction between them. Node size is proportional to its degree. (C) P-D chord diagram. The circle represents the selected pathways and diseases, and the color of the bands within the circle reflects the relationship between the pathways and the diseases.