Research Paper Volume 13, Issue 3 pp 4503—4521

Identification of therapeutic targets and prognostic biomarkers from the hnRNP family in invasive breast carcinoma

The relationship between the mRNA expression of hnRNPs and tumor stage, nodal metastasis status, and pathological subtypes of patients with TCGA-BRCA. (A) Heat map displaying the correlation between the expression of hnRNPs and tumor stage. The boxplot shows the correlation between HNRNPU expression and tumor stages. (B) Heat map displaying the association between the expression of hnRNPs and nodal metastasis status. The boxplot shows the association between HNRNPU expression and the nodal metastasis status. (C) Heat map displaying the correlation between the expression of hnRNPs and tumor pathological subtypes. The boxplot shows the association between hnRNPU expression and tumor pathological subtypes. Gray represents *P P P P

Figure 2. The relationship between the mRNA expression of hnRNPs and tumor stage, nodal metastasis status, and pathological subtypes of patients with TCGA-BRCA. (A) Heat map displaying the correlation between the expression of hnRNPs and tumor stage. The boxplot shows the correlation between HNRNPU expression and tumor stages. (B) Heat map displaying the association between the expression of hnRNPs and nodal metastasis status. The boxplot shows the association between HNRNPU expression and the nodal metastasis status. (C) Heat map displaying the correlation between the expression of hnRNPs and tumor pathological subtypes. The boxplot shows the association between hnRNPU expression and tumor pathological subtypes. Gray represents *P < 0.05, blue represents **P < 0.01, green represents ***P < 0.001, red represents ****P < 0.0001, and white represents no significant difference.