Research Paper Volume 13, Issue 3 pp 4503—4521

Identification of therapeutic targets and prognostic biomarkers from the hnRNP family in invasive breast carcinoma

Correlation between hnRNP mRNA expression and clinical prognosis in patients with BRCA. (A) Forest plots showing the correlation between the expression of hnRNPs and patient OS, as examined via Kaplan–Meier analysis. (B) High hnRNPD, hnRNPL, or SYNCRIP expression was significantly associated with poor OS. (C) Forest plots showing the association between the mRNA expression levels of hnRNPs and RFS. (D) High expression of HNRNPA0, PTBP1, HNRNPK, and SYNCRIP was significantly associated with poor RFS.

Figure 3. Correlation between hnRNP mRNA expression and clinical prognosis in patients with BRCA. (A) Forest plots showing the correlation between the expression of hnRNPs and patient OS, as examined via Kaplan–Meier analysis. (B) High hnRNPD, hnRNPL, or SYNCRIP expression was significantly associated with poor OS. (C) Forest plots showing the association between the mRNA expression levels of hnRNPs and RFS. (D) High expression of HNRNPA0, PTBP1, HNRNPK, and SYNCRIP was significantly associated with poor RFS.