Research Paper Volume 13, Issue 4 pp 5020—5033

Toxic effect of titanium dioxide nanoparticles on corneas in vitro and in vivo

class="figure-viewer-img"

Figure 2. Oxidative damage of TiO2 NPs to corneal endothelial cells. (A) Intracellular ROS of corneal endothelial cells with indicated treatment, bar = 40 μm. Detection of MDA content (B), SOD activity (C) and GSH-Px activity (D) in primary corneal endothelial cells with indicated treatment. **P<0.01 vs. control group, ***P<0.001 vs. control group, #P<0.05 vs. 25 μg/mL group, ##P<0.01 vs. 25 μg/mL group, &P<0.05 vs. 50 μg/mL group, &&P<0.01 vs. 50 μg/mL group, %P<0.05 vs. 100 μg/mL group, %%P<0.01 vs. H2O2 group, @P<0.05 vs. 50 μg/mL group, @@P<0.01 vs. H2O2 group.