Research Paper Volume 13, Issue 3 pp 4564—4589

Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis

Significant TICRR and PPIF-related genes and pathways in EC obtained by GSEA and GSVA. (A) The most involved pathways in high-expression group of TICRR obtained by GSEA analysis. (B) Transcriptional expression profiles of the significant genes were shown in a heat map. (C) The most common functional gene sets in high-expression group of PPIF by GSEA. (D) Transcriptional expression profiles of the significant genes related with PPIF were shown in a heat map. (E, F) GSVA-derived clustering heatmaps of differential pathways for TICRR and PPIF, respectively.

Figure 9. Significant TICRR and PPIF-related genes and pathways in EC obtained by GSEA and GSVA. (A) The most involved pathways in high-expression group of TICRR obtained by GSEA analysis. (B) Transcriptional expression profiles of the significant genes were shown in a heat map. (C) The most common functional gene sets in high-expression group of PPIF by GSEA. (D) Transcriptional expression profiles of the significant genes related with PPIF were shown in a heat map. (E, F) GSVA-derived clustering heatmaps of differential pathways for TICRR and PPIF, respectively.