Research Paper Volume 13, Issue 3 pp 4605—4616

Resveratrol alleviates bleomycin-induced pulmonary fibrosis via suppressing HIF-1α and NF-κB expression

Inhibition of HIF-1α partially reverses BLM-induced fibrosis. (A) The expression of HIF-1α in BEAS-2B cells with and without siRNA-HIF-1α transfection was measured by qRT-PCR. (B, C) The expression of inflammatory cytokines in different groups was measured by qRT-PCR. (D–F) The expression of fibrotic genes in different groups was measured by qRT-PCR.

Figure 6. Inhibition of HIF-1α partially reverses BLM-induced fibrosis. (A) The expression of HIF-1α in BEAS-2B cells with and without siRNA-HIF-1α transfection was measured by qRT-PCR. (B, C) The expression of inflammatory cytokines in different groups was measured by qRT-PCR. (DF) The expression of fibrotic genes in different groups was measured by qRT-PCR.