Granulosa cell apoptosis and oocyte maturation rate in PCOS and control group. (A1) Comparison of early and late apoptosis rate of granulosa cells in PCOS and control group by Annexin V FITC-A flow cytometry analysis. Results are mean±SD.*p < 0.05 vs. data of control group. (A2, A3) Examples of the Annexin V FITC-A flow cytometry analysis results of control group (A2) and PCOS group (A3). n=8 for each group. (B) PCOS patients had a lower oocyte maturation rate (number of mature oocytes/total retrieved oocytes) than control group. Results are mean±SEM. *p < 0.05 vs. data of control group. (C) Pearson correlation analysis showed a positive correlation between LNK (relative mRNA level, fold of GAPDH) and apoptosis. (D) LNK (relative mRNA level, fold of GAPDH) was negatively correlated with oocyte maturation rate.