Research Paper Volume 13, Issue 5 pp 6625—6633

Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation

Liraglutide promoted expression of Homer1 in H9C2 cells against H/R. H9C2 cells were pretreated with 200 nmol/L liraglutide or vehicle 30 min before H/R treatment, and the expression of Homer1 mRNA (A), protein (B, C), and intracellular localization (D, E) were examined by RT-qPCR, western blot and immunofluorescence staining.

Figure 4. Liraglutide promoted expression of Homer1 in H9C2 cells against H/R. H9C2 cells were pretreated with 200 nmol/L liraglutide or vehicle 30 min before H/R treatment, and the expression of Homer1 mRNA (A), protein (B, C), and intracellular localization (D, E) were examined by RT-qPCR, western blot and immunofluorescence staining.