Research Paper Volume 13, Issue 4 pp 5263—5283

Value of KPNA4 as a diagnostic and prognostic biomarker for hepatocellular carcinoma

Genetic mutations of KPNA4 and its associations with OS in HCC patients (cBioPortal). (A) Oncoprint of KPNA4 alterations in HCC. The overview of genomic alterations showed that the mutation rate of KPNA4 was 11%. (B) Alterations in KPNA4 poorly affect the prognosis of HCC patients. (C) Network view of KPNA4 and its altered neighboring genes in HCC. (D) GO functional enrichment and KEGG pathway analyses of KPNA4 and its frequently altered neighboring genes.

Figure 7. Genetic mutations of KPNA4 and its associations with OS in HCC patients (cBioPortal). (A) Oncoprint of KPNA4 alterations in HCC. The overview of genomic alterations showed that the mutation rate of KPNA4 was 11%. (B) Alterations in KPNA4 poorly affect the prognosis of HCC patients. (C) Network view of KPNA4 and its altered neighboring genes in HCC. (D) GO functional enrichment and KEGG pathway analyses of KPNA4 and its frequently altered neighboring genes.