Research Paper Volume 13, Issue 4 pp 5263—5283

Value of KPNA4 as a diagnostic and prognostic biomarker for hepatocellular carcinoma

Expression levels of KPNA4 and prognostic values in HCC patients. (A) KPNA4 mRNA level was increased in HCC tissues compared with normal tissues as measured by qRT-PCR. (B) KPNA4 protein level was increased in HCC tissues compared with normal tissues as measured by western blot. (C) KPNA4 expression by immunohistochemistry staining. (D) Semi-quantitative analysis of KPNA4 protein expression between cancerous specimens and non-cancerous parts. (E) ROC of KPNA4 level in HCC showing that elevated KPNA4 level correlated with HCC incidence. (F) High KPNA4 expression level correlated with poor OS.

Figure 9. Expression levels of KPNA4 and prognostic values in HCC patients. (A) KPNA4 mRNA level was increased in HCC tissues compared with normal tissues as measured by qRT-PCR. (B) KPNA4 protein level was increased in HCC tissues compared with normal tissues as measured by western blot. (C) KPNA4 expression by immunohistochemistry staining. (D) Semi-quantitative analysis of KPNA4 protein expression between cancerous specimens and non-cancerous parts. (E) ROC of KPNA4 level in HCC showing that elevated KPNA4 level correlated with HCC incidence. (F) High KPNA4 expression level correlated with poor OS.