Research Paper Volume 13, Issue 4 pp 5263—5283

Value of KPNA4 as a diagnostic and prognostic biomarker for hepatocellular carcinoma

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Figure 9. Expression levels of KPNA4 and prognostic values in HCC patients. (A) KPNA4 mRNA level was increased in HCC tissues compared with normal tissues as measured by qRT-PCR. (B) KPNA4 protein level was increased in HCC tissues compared with normal tissues as measured by western blot. (C) KPNA4 expression by immunohistochemistry staining. (D) Semi-quantitative analysis of KPNA4 protein expression between cancerous specimens and non-cancerous parts. (E) ROC of KPNA4 level in HCC showing that elevated KPNA4 level correlated with HCC incidence. (F) High KPNA4 expression level correlated with poor OS.