Research Paper Volume 13, Issue 4 pp 5553—5570

Melatonin protects against defects induced by Enniatin B1 during porcine early embryo development

Effect of melatonin on the expression of DNA methylation reprogramming related genes during the development of EB1-exposed embryos. (A–D) relative expression levels of Dnmt1, Dnmt3a, Tet1 and Tet3, respectively. CON, the control group. EB1, embryos treated with EB1. MT, embryos treated with melatonin. ME, embryos treated with both melatonin and EB1. a-dValues for a given group in columns with different superscripts differ significantly (p

Figure 6. Effect of melatonin on the expression of DNA methylation reprogramming related genes during the development of EB1-exposed embryos. (AD) relative expression levels of Dnmt1, Dnmt3a, Tet1 and Tet3, respectively. CON, the control group. EB1, embryos treated with EB1. MT, embryos treated with melatonin. ME, embryos treated with both melatonin and EB1. a-dValues for a given group in columns with different superscripts differ significantly (p < 0.05).