Research Paper Volume 13, Issue 4 pp 5607—5620

Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer

CRT is upregulated in GBC tissues and is associated with poor prognosis. (A) Relative mRNA expression of CRT in 32 paired adjacent and cancer tissues from patients with GBC. (B) Relative expression of CRT in tumor with a size C) IHC staining results for CRT in cholecystitis samples. (D) IHC staining results for CRT in adjacent peri-cancerous tissues. (E) IHC staining results for CRT in GBC cancer tissues (magnification x100). (F) Kaplan-Meier analyses of overall survival in 32 GBC patients based on CRT expression level of GBC tissues.*P

Figure 1. CRT is upregulated in GBC tissues and is associated with poor prognosis. (A) Relative mRNA expression of CRT in 32 paired adjacent and cancer tissues from patients with GBC. (B) Relative expression of CRT in tumor with a size <5cm and ≥5cm in patients with GBC. (C) IHC staining results for CRT in cholecystitis samples. (D) IHC staining results for CRT in adjacent peri-cancerous tissues. (E) IHC staining results for CRT in GBC cancer tissues (magnification x100). (F) Kaplan-Meier analyses of overall survival in 32 GBC patients based on CRT expression level of GBC tissues.*P<0.05 vs. adjacent tissue or vs. tumor with a size<5cm. CRT, calreticulin; GBC, gallbladder cancer.