Research Paper Volume 13, Issue 4 pp 5698—5717

Identification of novel candidate biomarkers for pancreatic adenocarcinoma based on TCGA cohort

Diagnostic significance of three key genes and validation of the expression levels of key genes. (A–C) ROC curves and AUC were utilized to evaluate the specificity and sensitivity of key genes on PAAD diagnosis. (D–G) Data from Oncomine datasets confirmed that ITGB1, ITGB5, and OSMR were significantly increased in PAAD tissues compared with normal controls. ROC, receiver operating characteristic; AUC, area under the curve; PAAD, pancreatic adenocarcinoma.

Figure 6. Diagnostic significance of three key genes and validation of the expression levels of key genes. (AC) ROC curves and AUC were utilized to evaluate the specificity and sensitivity of key genes on PAAD diagnosis. (DG) Data from Oncomine datasets confirmed that ITGB1, ITGB5, and OSMR were significantly increased in PAAD tissues compared with normal controls. ROC, receiver operating characteristic; AUC, area under the curve; PAAD, pancreatic adenocarcinoma.