COVID-19 Research Paper Volume 13, Issue 4 pp 4794—4810

Association of D-dimer elevation with inflammation and organ dysfunction in ICU patients with COVID-19 in Wuhan, China: a retrospective observational study

Heat maps of the correlation between the D-dimer level and laboratory results. (A) The number of patients with abnormalities in 46 parameters varied according to D-dimer level at the time of ICU admission. (B) The number of patients with abnormalities in 52 parameters varied according to D-dimer level during ICU treatment. D0: D-dimerSupplementary Table 3, Supplementary files.

Figure 1. Heat maps of the correlation between the D-dimer level and laboratory results. (A) The number of patients with abnormalities in 46 parameters varied according to D-dimer level at the time of ICU admission. (B) The number of patients with abnormalities in 52 parameters varied according to D-dimer level during ICU treatment. D0: D-dimer<1.5μg/mL, D1: 1.5≤D-dimer<10μg/mL, D2: 10≤D-dimer<40μg/mL, D3: D-dimer≥40μg/mL. Normal: the result is within the normal range, High: the result is beyond the normal range, Low: the result is below the normal range. *P<0.05, **P<0.01, ***P<0.001 among these 4 groups, abbreviation and range of normal values can be found in Supplementary Table 3, Supplementary files.