Research Paper Volume 13, Issue 4 pp 5718—5747

Comprehensive analysis of macrophage-related multigene signature in the tumor microenvironment of head and neck squamous cancer

Relationship between FANCE and immune checkpoint related genes. The larger the area of the circle, the darker the color and the greater the correlation. The asterisk in the circle indicates statistical significance. The results showed that there was a significant correlation (*P

Figure 12. Relationship between FANCE and immune checkpoint related genes. The larger the area of the circle, the darker the color and the greater the correlation. The asterisk in the circle indicates statistical significance. The results showed that there was a significant correlation (*P<0.05) between the expression of FANCE and reported immune-related genes (CD274, HAVCR2, CTLA4, LAG3, PDCD1, TIGIT), but no significant co-expression between PDCD1LG2 and FANCE relationship.