Research Paper Volume 13, Issue 4 pp 5804—5823

Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture

Functional annotation of DEGs in JFs following treatment with MIF. (A, B) Bar graphs of DEGs following treatment with 2 μg/mL recombinant MIF for 24 h (A) and 48 h (B). (C) Integration of DEGs at 24 and 48 h. (D, E) Top 30 most significantly enriched groups for the DEGs related to pathways following treatment with 2 μg/mL recombinant MIF for 24 h (D) and 48 h (E). (F) Top 30 most significantly enriched groups for integrated DEGs related to pathways.

Figure 7. Functional annotation of DEGs in JFs following treatment with MIF. (A, B) Bar graphs of DEGs following treatment with 2 μg/mL recombinant MIF for 24 h (A) and 48 h (B). (C) Integration of DEGs at 24 and 48 h. (D, E) Top 30 most significantly enriched groups for the DEGs related to pathways following treatment with 2 μg/mL recombinant MIF for 24 h (D) and 48 h (E). (F) Top 30 most significantly enriched groups for integrated DEGs related to pathways.