Research Paper Volume 13, Issue 2 pp 1671—1685

Dietary administration of cumin-derived cuminaldehyde induce neuroprotective and learning and memory enhancement effects to aging mice

Effect of CA on mRNA expressions of Bdnf (A), Icam (B), ApoE (C) and IL-6 (D) in C57BL/6J mice brain. The mRNA expression of all genes were normalized to GAPDH mRNA expression and expressed with respect to the negative control (aged water-treated group). C57BL/6J mice were administrated with CA for 30 days. The control group was administered with distilled water. Each bar represents the mean ± SD. * P

Figure 7. Effect of CA on mRNA expressions of Bdnf (A), Icam (B), ApoE (C) and IL-6 (D) in C57BL/6J mice brain. The mRNA expression of all genes were normalized to GAPDH mRNA expression and expressed with respect to the negative control (aged water-treated group). C57BL/6J mice were administrated with CA for 30 days. The control group was administered with distilled water. Each bar represents the mean ± SD. * P < 0.05, ** P < 0.01 as compared to negative control group. NC: negative control (aged water-treated group), PC: positive control (young water-treated group), CA: Cuminaldehyde treated group.