Research Paper Volume 13, Issue 4 pp 6010—6024

Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis

The expression of lncRNA LINC00662 is elevated in the plasma exosome of NSCLC patients. (A) The expression levels of lncRNA LINC00662 were measured by qPCR in the plasma exosome from NSCLC patients (n=50). (B) The expression levels of lncRNA LINC00662 were measured by qPCR in the NSCLC patient tissues (n=50) and the adjacent normal tissues (n=50). (C) The characteristics of exosomes were analyzed by the transmission electron microscopy (TEM) in the NSCLC patients. (D) The expression of TSG101, CD63, and Grp94 was tested by Western blot analysis in the exosome from NSCLC patients.

Figure 1. The expression of lncRNA LINC00662 is elevated in the plasma exosome of NSCLC patients. (A) The expression levels of lncRNA LINC00662 were measured by qPCR in the plasma exosome from NSCLC patients (n=50). (B) The expression levels of lncRNA LINC00662 were measured by qPCR in the NSCLC patient tissues (n=50) and the adjacent normal tissues (n=50). (C) The characteristics of exosomes were analyzed by the transmission electron microscopy (TEM) in the NSCLC patients. (D) The expression of TSG101, CD63, and Grp94 was tested by Western blot analysis in the exosome from NSCLC patients.