Research Paper Volume 13, Issue 2 pp 1686—1691

Shorter telomeres in children with severe asthma, an indicative of accelerated aging

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Figure 1. Shorter telomeres in STRA children. (A) Relative telomere length (rTL) measured in whole blood from HC (n=126), MA (n=124) and STRA (n=17). (B) Augmented levels of eotaxin-1 in STRA children (n=16) compared to HC (n=24) and MA (n=24). (C) Eotaxin-1 is inversely correlated with rTL only in the STRA group. Data presented as [median; IQR (25-75)]. Kruskal-Wallis test followed by Dunn's multiple comparisons and Pearson correlation test. Significant differences were considered when p<0.05 (*); p<0.01 (**). NS: non-significant.