Research Paper Volume 13, Issue 5 pp 6804—6819
Transcription factor ELK1 accelerates aerobic glycolysis to enhance osteosarcoma chemoresistance through miR-134/PTBP1 signaling cascade
Figure 8. The mechanism graph of transcription factor ELK1 in chemoresistance in osteosarcoma. ELK1 promotes aerobic glycolysis by inhibiting miR-134 and upregulating PTBP1 expression, thus enhancing chemotherapeutic resistance in osteosarcoma.