Research Paper Volume 13, Issue 5 pp 6945—6956

Silencing of miR-483-5p alleviates postmenopausal osteoporosis by targeting SATB2 and PI3K/AKT pathway

miR-483-5p-SATB2 axis regulated the progress of osteoporosis in OVX rats. (A) qRT-PCR results for miR-483-5p expression. (B) qRT-PCR results for SATB2 expression. (C) The bone mineral density (BMD) of femurs. (D) The maximum bending stress of femurs. (E) The maximum load of femurs. (F) The elasticity modulus of femurs. Data were presented as mean ± SD. a p b p c p

Figure 6. miR-483-5p-SATB2 axis regulated the progress of osteoporosis in OVX rats. (A) qRT-PCR results for miR-483-5p expression. (B) qRT-PCR results for SATB2 expression. (C) The bone mineral density (BMD) of femurs. (D) The maximum bending stress of femurs. (E) The maximum load of femurs. (F) The elasticity modulus of femurs. Data were presented as mean ± SD. a p < 0.05 versus control group, b p < 0.05 versus model group, c p < 0.05 versus inhibitor group.