Research Paper Volume 13, Issue 5 pp 7120—7132

Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway

Differential protein expression and KEGG pathway analysis. (A) PANC-1 cells were treated with normoxic or hypoxic PSC-derived exosomes prior to iTRAQ-based analysis of protein profiles. (B) KEGG analysis results showing the top-5 pathways enriched in the differentially expressed proteins identified in PANC-1 cells treated with hypoxic PSC-derived exosomes.

Figure 6. Differential protein expression and KEGG pathway analysis. (A) PANC-1 cells were treated with normoxic or hypoxic PSC-derived exosomes prior to iTRAQ-based analysis of protein profiles. (B) KEGG analysis results showing the top-5 pathways enriched in the differentially expressed proteins identified in PANC-1 cells treated with hypoxic PSC-derived exosomes.