Research Paper Volume 13, Issue 5 pp 7120—7132

Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway

PTEN is a target of miR-4465 and miR-616-3p. (A) Identification of PTEN as a miR-4465 and miR-616-3p target by TargetScan. (B) Dual-luciferase reporter assay results indicating interaction between both miR-4465 and miR-616-3p and the WT 3’UTR of PTEN.

Figure 7. PTEN is a target of miR-4465 and miR-616-3p. (A) Identification of PTEN as a miR-4465 and miR-616-3p target by TargetScan. (B) Dual-luciferase reporter assay results indicating interaction between both miR-4465 and miR-616-3p and the WT 3’UTR of PTEN.