Research Paper Volume 13, Issue 5 pp 7314—7329

Levodopa affects spike and local field synchronisation in the pedunculopontine nucleus of a rat model of Parkinson’s disease

Measurement of the coherence value between spikes and local field potential (LFP) in the pedunculopontine nucleus (PPN). (A) Frequency-coherence value plots in resting Type A neurones. (B) Frequency-coherence value plots in resting Type B neurones. (C) Statistical results of coherence value in resting Type A neurones. (D) Statistical results of coherence value in resting Type B neurones. (E) Frequency-coherence value plots of Type A neurones in locomotion state. (F) Frequency-coherence value plots of Type B neurones in locomotion state. (G) Statistical results of coherence value obtained in Type A neurones in locomotion state. (H) Statistical results of coherence value obtained in Type B neurones in locomotion state. The frequency bands with the most noticeable changes are highlighted via blue boxes. *p

Figure 4. Measurement of the coherence value between spikes and local field potential (LFP) in the pedunculopontine nucleus (PPN). (A) Frequency-coherence value plots in resting Type A neurones. (B) Frequency-coherence value plots in resting Type B neurones. (C) Statistical results of coherence value in resting Type A neurones. (D) Statistical results of coherence value in resting Type B neurones. (E) Frequency-coherence value plots of Type A neurones in locomotion state. (F) Frequency-coherence value plots of Type B neurones in locomotion state. (G) Statistical results of coherence value obtained in Type A neurones in locomotion state. (H) Statistical results of coherence value obtained in Type B neurones in locomotion state. The frequency bands with the most noticeable changes are highlighted via blue boxes. *p < 0.05, **p < 0.01 in comparison to the control group.