Research Paper Volume 13, Issue 5 pp 7361—7381

Artificial intelligence prediction model for overall survival of clear cell renal cell carcinoma based on a 21-gene molecular prognostic score system

Mutations and copy number variations in the three subgroups stratified by mPS system. (A–C) Distribution and phenotype of common gene mutations in the three subgroups stratified by mPS system: (A) low-mPS group (mPSB) median-mPS group (22≤mPSC) high-mPS group (mPS>30). (D) The levels of amplification and deletion of chromosome arms of the three subgroups stratified by mPS system. Objects with pentagrams indicate there is a significant difference in the frequency distribution among the three subgroup (P E–G) The copy number variations located on minimal common regions (MCRs) of the three subgroups stratified by mPS system: (E) low-mPS group (mPSF) median-mPS group (22≤mPSG) high-mPS group (mPS≥30).

Figure 7. Mutations and copy number variations in the three subgroups stratified by mPS system. (AC) Distribution and phenotype of common gene mutations in the three subgroups stratified by mPS system: (A) low-mPS group (mPS<22); (B) median-mPS group (22≤mPS<30); (C) high-mPS group (mPS>30). (D) The levels of amplification and deletion of chromosome arms of the three subgroups stratified by mPS system. Objects with pentagrams indicate there is a significant difference in the frequency distribution among the three subgroup (P < 0.01); (EG) The copy number variations located on minimal common regions (MCRs) of the three subgroups stratified by mPS system: (E) low-mPS group (mPS<22); (F) median-mPS group (22≤mPS<30); (G) high-mPS group (mPS≥30).