Research Paper Volume 13, Issue 4 pp 6091—6102

Circ_0000527 promotes osteosarcoma cell progression through modulating miR-646/ARL2 axis

miR-646 expression was downregulated in osteosarcoma. (A) miR-646 was downregulated in osteosarcoma specimens compared to non-tumor specimens. The expression of miR-646 was detected by a qRT-PCR assay. (B) The level of miR-646 was upregulated in 17 cases (17/30, 56.7%) compared to non-tumor specimens. (C) The level of circ

Figure 7. miR-646 expression was downregulated in osteosarcoma. (A) miR-646 was downregulated in osteosarcoma specimens compared to non-tumor specimens. The expression of miR-646 was detected by a qRT-PCR assay. (B) The level of miR-646 was upregulated in 17 cases (17/30, 56.7%) compared to non-tumor specimens. (C) The level of circ_0000527 was negatively correlated with miR-646 expression in osteosarcoma specimens.