Research Paper Volume 13, Issue 4 pp 6144—6155

Effect of age and isolated systolic or diastolic hypertension on target organ damage in non-dialysis patients with chronic kidney disease

Relationship between left ventricular mass index (LVMI), the Log (estimated glomerular filtration rate) (eGFR), and the Log (albumin creatinine ratio) (ACR) and blood pressure types in different age groups. In patients under 60 years old, adjusted variables for LVMI include gender, age, BMI, current smoker, diabetes mellitus, CVD history, antihypertensive drugs, hemoglobin, uric acid, HDL-C, LDL-C, serum albumin, serum phosphate, iPTH, eGFR, ISH, IDH, SDH; adjusted variables for Log (eGFR) include gender, age, BMI, current smoker, alcohol intake, diabetes mellitus, hyperlipidemia, CVD history, antihypertensive drugs, hemoglobin, uric acid, total cholesterol, HDL-C, LDL-C, serum phosphate, iPTH, ISH, IDH, SDH; adjusted variables for Log (ACR) include gender, age, alcohol intake, diabetes mellitus, antihypertensive drugs, hemoglobin, uric acid, triglyceride, total cholesterol, HDL-C, LDL-C, serum albumin, serum phosphate, iPTH, eGFR, ISH, IDH, SDH. In patients at and above 60 years old, adjusted variables for LVMI include gender, current smoker, hyperlipidemia, CVD history, antihypertensive drugs, hemoglobin, uric acid, HDL-C, serum phosphate, iPTH, eGFR, ISH, IDH, SDH; adjusted variables for Log (eGFR) include gender, age, BMI, hyperlipidemia, antihypertensive drugs, hemoglobin, uric acid, triglyceride, HDL-C, LDL-C, serum phosphate, iPTH, ISH, IDH, SDH; adjusted variables for Log (ACR) include gender, diabetes mellitus, antihypertensive drugs, hemoglobin, HDL-C, LDL-C, serum albumin, serum calcium, serum phosphate, iPTH, eGFR, ISH, IDH, SDH. BMI, body mass index; CVD, cardiovascular disease; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; iPTH, intact parathyroid hormone; NM, normotension; ISH, isolated systolic hypertension; IDH, isolated diastolic hypertension; SDH, systolic and diastolic hypertension; LVMI, left ventricular mass index; eGFR, estimated glomerular filtration rate; ACR, albumin creatinine ratio. * P

Figure 1. Relationship between left ventricular mass index (LVMI), the Log (estimated glomerular filtration rate) (eGFR), and the Log (albumin creatinine ratio) (ACR) and blood pressure types in different age groups. In patients under 60 years old, adjusted variables for LVMI include gender, age, BMI, current smoker, diabetes mellitus, CVD history, antihypertensive drugs, hemoglobin, uric acid, HDL-C, LDL-C, serum albumin, serum phosphate, iPTH, eGFR, ISH, IDH, SDH; adjusted variables for Log (eGFR) include gender, age, BMI, current smoker, alcohol intake, diabetes mellitus, hyperlipidemia, CVD history, antihypertensive drugs, hemoglobin, uric acid, total cholesterol, HDL-C, LDL-C, serum phosphate, iPTH, ISH, IDH, SDH; adjusted variables for Log (ACR) include gender, age, alcohol intake, diabetes mellitus, antihypertensive drugs, hemoglobin, uric acid, triglyceride, total cholesterol, HDL-C, LDL-C, serum albumin, serum phosphate, iPTH, eGFR, ISH, IDH, SDH. In patients at and above 60 years old, adjusted variables for LVMI include gender, current smoker, hyperlipidemia, CVD history, antihypertensive drugs, hemoglobin, uric acid, HDL-C, serum phosphate, iPTH, eGFR, ISH, IDH, SDH; adjusted variables for Log (eGFR) include gender, age, BMI, hyperlipidemia, antihypertensive drugs, hemoglobin, uric acid, triglyceride, HDL-C, LDL-C, serum phosphate, iPTH, ISH, IDH, SDH; adjusted variables for Log (ACR) include gender, diabetes mellitus, antihypertensive drugs, hemoglobin, HDL-C, LDL-C, serum albumin, serum calcium, serum phosphate, iPTH, eGFR, ISH, IDH, SDH. BMI, body mass index; CVD, cardiovascular disease; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; iPTH, intact parathyroid hormone; NM, normotension; ISH, isolated systolic hypertension; IDH, isolated diastolic hypertension; SDH, systolic and diastolic hypertension; LVMI, left ventricular mass index; eGFR, estimated glomerular filtration rate; ACR, albumin creatinine ratio. * P <0.05.