COVID-19 Research Paper Volume 13, Issue 4 pp 4811—4830

Chemical composition and pharmacological mechanism of ephedra-glycyrrhiza drug pair against coronavirus disease 2019 (COVID-19)

Molecular models of the selected compounds binding to the target proteins. (A) The docking mode and interactions between xambioona and ACE2, (B) Licorice glycoside E and S protein, (C) Licorice glycoside E and Mpro. The light red stick represents the binding energy of xambioona, the light blue stick represents the binding energy of licorice glycoside E, and the green dotted line represents the hydrogen bond.

Figure 9. Molecular models of the selected compounds binding to the target proteins. (A) The docking mode and interactions between xambioona and ACE2, (B) Licorice glycoside E and S protein, (C) Licorice glycoside E and Mpro. The light red stick represents the binding energy of xambioona, the light blue stick represents the binding energy of licorice glycoside E, and the green dotted line represents the hydrogen bond.