Research Paper Volume 13, Issue 6 pp 8276—8289

Identification and validation of a two-gene metabolic signature for survival prediction in patients with kidney renal clear cell carcinoma

Expression levels and prognostic value of the signature genes. (A) Expression profiles of RRM2 and ALDH6A1 transcripts in the Oncomine database. (B) Expression profiles of RRM2 and ALDH6A1 transcripts in various cancers on the TIMER database. (C) Expression profiles of RRM2 and ALDH6A1 transcripts in the GEPIA database. (D) Univariate survival analysis (Kaplan-Meier curves) for RRM2 and ALDH6A1. (E) Immunohistochemistry images of RRM2 and ALDH6A1 expression in KIRC and normal kidney tissues. Examples were retrieved from the Human Protein Atlas database. (F) Verification of RM2 and ALDH6A1 expression in KIRC and normal tissues in the GSE53757 database. (G) Verification of RM2 and ALDH6A1 expression in KIRC and normal tissues in the GSE66270 database.

Figure 7. Expression levels and prognostic value of the signature genes. (A) Expression profiles of RRM2 and ALDH6A1 transcripts in the Oncomine database. (B) Expression profiles of RRM2 and ALDH6A1 transcripts in various cancers on the TIMER database. (C) Expression profiles of RRM2 and ALDH6A1 transcripts in the GEPIA database. (D) Univariate survival analysis (Kaplan-Meier curves) for RRM2 and ALDH6A1. (E) Immunohistochemistry images of RRM2 and ALDH6A1 expression in KIRC and normal kidney tissues. Examples were retrieved from the Human Protein Atlas database. (F) Verification of RM2 and ALDH6A1 expression in KIRC and normal tissues in the GSE53757 database. (G) Verification of RM2 and ALDH6A1 expression in KIRC and normal tissues in the GSE66270 database.