Research Paper Volume 13, Issue 6 pp 8320—8334

Celecoxib alleviates zinc deficiency-promoted colon tumorigenesis through suppressing inflammation

ZD promoted the inflammation. (A) ZD induced the protein pro-inflammatory mediators in the colon. CCL2, CXCL2, CXCL5, IL-1β, IL6, and TNF-α protein were measured by ELISA. (B) ZD induced the protein pro-inflammatory mediators in serum. CCL2, CXCL2, CXCL5, IL-1β, IL6, and TNF-α protein were measured by ELISA. Horizontal bars indicated the average protein levels. *P P P

Figure 4. ZD promoted the inflammation. (A) ZD induced the protein pro-inflammatory mediators in the colon. CCL2, CXCL2, CXCL5, IL-1β, IL6, and TNF-α protein were measured by ELISA. (B) ZD induced the protein pro-inflammatory mediators in serum. CCL2, CXCL2, CXCL5, IL-1β, IL6, and TNF-α protein were measured by ELISA. Horizontal bars indicated the average protein levels. *P < 0.05, **P < 0.01, and ***P < 0.001 vs ZS group, n=6.