Research Paper Volume 13, Issue 5 pp 7644—7659

Platelets transport β-amyloid from the peripheral blood into the brain by destroying the blood-brain barrier to accelerate the process of Alzheimer's disease in mouse models

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Figure 4. Effects of tail vein injection of plasma or platelets on AD related indexes of blood and brain tissue in mice. (E) Brain image of a C57+APP/PS1 platelet mouse by MRI. (F) Quantity of platelets. (G) Volume of platelets. Each group included 8 mice. No significant differences were observed between groups. (H) Aβ1-40, Aβ1-42 and tau protein levels per unit of platelets. (I) Aβ1-40 levels in platelets. (J) Aβ1-42 levels in platelets. (K) Tau levels in platelets. Each group included 8 mice. *P<0.05 compared with C57+NS and #P<0.05 compared with C57+APP/PS1 platelets.