Research Paper Volume 13, Issue 6 pp 8524—8540

Combination CTLA-4 immunoglobulin treatment and ultrasound microbubble-mediated exposure improve renal function in a rat model of diabetic nephropathy

Comparison of expression of podocin, nephrin, and B7-1 proteins in rat kidneys. Data are expressed as means ± SD. IOD / area of podocin, nephrin, and B7-1: integrated optical density value per unit area of podocin, nephrin, and B7-1. (A) podocin, * P B) nephrin, * P C) B7-1, * P

Figure 10. Comparison of expression of podocin, nephrin, and B7-1 proteins in rat kidneys. Data are expressed as means ± SD. IOD / area of podocin, nephrin, and B7-1: integrated optical density value per unit area of podocin, nephrin, and B7-1. (A) podocin, * P <0.05 vs control, #P <0.05 vs CTLA-4-Ig + UM, Δ P <0.05 vs CTLA-4-Ig; (B) nephrin, * P <0.05 vs control, #P <0.05 vs CTLA-4-Ig + UM, Δ P <0.05 vs CTLA-4-Ig; (C) B7-1, * P <0.05 vs control, #P <0.05 vs CTLA-4-Ig + UM, Δ P <0.05 vs CTLA-4-Ig.