Research Paper Volume 13, Issue 6 pp 8524—8540

Combination CTLA-4 immunoglobulin treatment and ultrasound microbubble-mediated exposure improve renal function in a rat model of diabetic nephropathy

Comparison of the expression of Fn, collagen I, and talin in rat kidneys. Data are expressed as means ± standard deviation, IOD / area of Fn, Collagen I, and Talin: integrated optical density value per unit area of Fn, Collagen I, and Talin. (A) Fn, * P B) Collagen I, * P C) Talin, * P

Figure 6. Comparison of the expression of Fn, collagen I, and talin in rat kidneys. Data are expressed as means ± standard deviation, IOD / area of Fn, Collagen I, and Talin: integrated optical density value per unit area of Fn, Collagen I, and Talin. (A) Fn, * P <0.05 vs control, #P <0.05 vs CTLA-4-Ig + UM, Δ P <0.05 vs CTLA-4-Ig; (B) Collagen I, * P <0.05 vs control, #P <0.05 vs CTLA-4-Ig + UM, Δ P <0.05 vs CTLA-4-Ig; (C) Talin, * P <0.05 vs control, #P <0.05 vs CTLA-4-Ig + UM, Δ P <0.05 vs CTLA-4-Ig.