Research Paper Volume 13, Issue 6 pp 8541—8562

TACC3 is a prognostic biomarker for kidney renal clear cell carcinoma and correlates with immune cell infiltration and T cell exhaustion

Gene sets enriched in the high TACC3 expression phenotype using GSEA. The results showing immune-associated pathways: cytokine-cytokine receptor interaction (A), intestinal immune network for IgA production (C), natural killer cell-mediated cytotoxicity (E), primary immunodeficiency (G), T cell receptor signaling (H), antigen processing and presentation (J) and B cell receptor signaling (K); p53 signaling pathway (F); JAK/STAT signaling pathway (D); DNA repair-associated pathways: homologous recombination (B), DNA replication (I), and base excision repair (L).

Figure 9. Gene sets enriched in the high TACC3 expression phenotype using GSEA. The results showing immune-associated pathways: cytokine-cytokine receptor interaction (A), intestinal immune network for IgA production (C), natural killer cell-mediated cytotoxicity (E), primary immunodeficiency (G), T cell receptor signaling (H), antigen processing and presentation (J) and B cell receptor signaling (K); p53 signaling pathway (F); JAK/STAT signaling pathway (D); DNA repair-associated pathways: homologous recombination (B), DNA replication (I), and base excision repair (L).