Research Paper Volume 13, Issue 4 pp 4895—4910

Cholecalciferol (vitamin D3) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes

VD3 does not protect myotubes against atrophy induced by dexamethasone. (A) Myotube diameters were measured after 24 h treatment with 5 μM dexamethasone (DEXA) alone or in combination with 100 nM VD3. (B) Expression of Atrogin-1 (Fbxo32) was assessed by real-time RT-PCR. Data are presented as the mean ± SEM. ** P

Figure 6. VD3 does not protect myotubes against atrophy induced by dexamethasone. (A) Myotube diameters were measured after 24 h treatment with 5 μM dexamethasone (DEXA) alone or in combination with 100 nM VD3. (B) Expression of Atrogin-1 (Fbxo32) was assessed by real-time RT-PCR. Data are presented as the mean ± SEM. ** P <0.01.