Research Paper Volume 13, Issue 6 pp 8720—8736

Parvalbumin interneuron-mediated neural disruption in an animal model of postintensive care syndrome: prevention by fluoxetine

Fluoxetine treatment attenuated IL-6 level after combined stress. (A) Schematic timeline of the experimental procedure. (B–K) Quantification of inflammatory mediators in the hippocampus. Data are shown as mean ± SEM (n = 6), *P #P

Figure 2. Fluoxetine treatment attenuated IL-6 level after combined stress. (A) Schematic timeline of the experimental procedure. (B–K) Quantification of inflammatory mediators in the hippocampus. Data are shown as mean ± SEM (n = 6), *P < 0.05 vs control group, #P < 0.05 vs LS group. Con, control; LPS, lipopolysaccharide; Flu, fluoxetine; LS, LPS + stress.