Figure 3. Immune feature selection based on the LASSO Cox regression model. (A) Optimal feature subsets based on the minimum criteria with 10-fold cross-validation of the LASSO regression. The vertical dashed lines represent the optimal values using the minimum criteria and the 1-standard error (SE) of the minimum criteria. The λ selected with 10-fold cross-validation (minimum criteria) was 0.039, and log (λ) was -3.245. (B) Regression coefficient profiles of 22 immune signatures in the LASSO model. The vertical dotted line is the optimal λ selected with 10-fold cross-validation, which resulted in 12 non-zero coefficients.