Research Paper Volume 13, Issue 6 pp 8777—8796

Comprehensive analysis of expression and prognostic value of the claudin family in human breast cancer

Analysis of alterations in claudins in breast cancer (using cBioPortal for Cancer Genomics). (A) OncoPrint of the TCGA dataset in cBioPortal. (B) OncoPrint of the METABRIC dataset in cBioPortal. (C) DFS analysis in cases with or without alterations in claudin genes of the TCGA dataset. (D) OS analysis in cases with or without alterations in claudin genes of the TCGA dataset. (E) OS analysis in cases with or without alterations in claudin genes of the METABRIC dataset. OncoPrint represents the distribution and proportion of samples with different kinds of alterations in the claudin family. Abbreviations: DFS, disease/progression-free survival; OS, overall survival.

Figure 7. Analysis of alterations in claudins in breast cancer (using cBioPortal for Cancer Genomics). (A) OncoPrint of the TCGA dataset in cBioPortal. (B) OncoPrint of the METABRIC dataset in cBioPortal. (C) DFS analysis in cases with or without alterations in claudin genes of the TCGA dataset. (D) OS analysis in cases with or without alterations in claudin genes of the TCGA dataset. (E) OS analysis in cases with or without alterations in claudin genes of the METABRIC dataset. OncoPrint represents the distribution and proportion of samples with different kinds of alterations in the claudin family. Abbreviations: DFS, disease/progression-free survival; OS, overall survival.