Research Paper Volume 13, Issue 7 pp 9582—9591

LCZ696 ameliorates lipopolysaccharide-induced endothelial injury

LCZ696 suppresses LPS-induced attachment of U937 monocytes to HUVECs

Figure 7. LCZ696 suppresses LPS-induced attachment of U937 monocytes to HUVECs. Cells were stimulated with LPS (1 μg/mL) in the presence or absence of LCZ696 (20 μM) for 24 hours. Attachment of U937 monocytes to HUVECs was measured by 5-chloromethylfluorescein diacetate (***P < 0.005 vs. control group; ##, ###P < 0.01, 0.005 vs. LPS group).