Figure 4. JB-3-22 treatment elevated the acetylation levels of histone H4 lysine sites in porcine oocytes. (A) Images of acetylated H4K16 in control and JB-3-22-treated oocytes at MI /MII stages. (B) Images of acetylated H4K5 in control and JB-3-22-treated oocytes at MI /MII stages. (C) Images of acetylated H4K12 in control and JB-3-22 treated oocytes at MI /MII stages. The results represent the mean ± standard deviation of three independent experiments. ** P < 0.01. Scale bar, 100 μm.