Research Paper Volume 13, Issue 5 pp 6359—6374

Mucosal microRNAs relate to age and severity of disease in ulcerative colitis

Comparison of miRNA expression levels and Geboes score in pediatric and adult patients with ulcerative colitis. The correlation is presented by Spearman’s rho and compares expression levels of miRNA (assessed by RT-qPCR) and Geboes score from the rectal mucosa. Because the miR-21 expression was increased in adult patient, pediatric and adult patients are presented separately for the comparison of miR-21. (A) pediatric miR-21 (rho=-0.04, p=0.8). (B) adult miR-21 (rho=0.19, p=0.37). (C) miR-31 (rho=-0.29, p=0.03). (D) miR-142 (rho=-0.04, p=0.8). (E) miR-155 (rho=-0.21, p=0.15).

Figure 1. Comparison of miRNA expression levels and Geboes score in pediatric and adult patients with ulcerative colitis. The correlation is presented by Spearman’s rho and compares expression levels of miRNA (assessed by RT-qPCR) and Geboes score from the rectal mucosa. Because the miR-21 expression was increased in adult patient, pediatric and adult patients are presented separately for the comparison of miR-21. (A) pediatric miR-21 (rho=-0.04, p=0.8). (B) adult miR-21 (rho=0.19, p=0.37). (C) miR-31 (rho=-0.29, p=0.03). (D) miR-142 (rho=-0.04, p=0.8). (E) miR-155 (rho=-0.21, p=0.15).