Research Paper Volume 13, Issue 6 pp 8960—8974

Exercise in mice ameliorates high-fat diet-induced nonalcoholic fatty liver disease by lowering HMGCS2

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Figure 3. Exercise ameliorated liver histological changes and steatosis. (A) Hepatic steatosis and ballooning area (A1) determined by H&E and (B) Oil Red O staining for hepatic fat (scale: 50 μm). (C, D) The serum levels of ALT and AST in mice induced by HFD. Data are presented as mean ± SD, n = 6. * P < 0.05 vs ND+SED and † P < 0.05 vs HFD+SED.