Research Paper Volume 13, Issue 6 pp 8960—8974
Exercise in mice ameliorates high-fat diet-induced nonalcoholic fatty liver disease by lowering HMGCS2
Figure 6. Exercise-dependent reduction of HFD-induced expression of HMGCS2 and Wnt3a/β-catenin in hepatic tissue. (A) Representative western blot for HMGCS2 in mouse liver. (B) Quantification of HMGCS2 protein levels relative to GAPDH. (C) Representative western blot for Wnt3a/β-catenin in mouse liver. (D, E) Quantification of Wnt3a and β-catenin protein levels relative to GAPDH. (F) Representative western blot for p-AMPK in mouse liver. (G) Quantification of p-AMPK protein levels relative to AMPK. Data are presented as mean ± SD, n = 6. * P < 0.05 vs ND+SED and † P < 0.05 vs HFD+SED.