Research Paper Volume 13, Issue 7 pp 9348—9372

miR-30c-1 encourages human corneal endothelial cells to regenerate through ameliorating senescence

miR-30c-1 ameliorates TGF-β1-induced senescence. (A) Representative images of senescence-β-galactosidase (SA-β-gal) staining. (B) The percentage of SA-β-gal positive cells was quantified. (C) Intracellular oxidative stress levels measured by MitoSOX probe. (D) Representative images of p-p38 and p38. (E) Activation of p38 was quantified. (F) Representative images of p63. (G) p63 level was quantified. *statistically significant.

Figure 5. miR-30c-1 ameliorates TGF-β1-induced senescence. (A) Representative images of senescence-β-galactosidase (SA-β-gal) staining. (B) The percentage of SA-β-gal positive cells was quantified. (C) Intracellular oxidative stress levels measured by MitoSOX probe. (D) Representative images of p-p38 and p38. (E) Activation of p38 was quantified. (F) Representative images of p63. (G) p63 level was quantified. *statistically significant.